558.274—Hygromycin B.

(a) Approvals. (1) Type A medicated articles: 2.4 and 8 grams per pound to 000986 in § 510.600(c) of this chapter for use as in paragraph (c) of this section.

(2) 2.4 grams per pound to No. 051311 in § 510.600(c) of this chapter for use in swine feed as in paragraph (c)(1)(ii) of this section.

(3) [Reserved]

(4) 0.6 gram per pound to 017790 and 043733 in § 510.600(c) of this chapter for use in chickens as in paragraph (c)(1)(i) of this section and in swine as in paragraph (c)(1)(ii) of this section.

(5) -(6) [Reserved]

(7) 2.4 grams per pound to No. 012286 in § 510.600(c) of this chapter for use in chickens as in paragraph (c)(1)(i) and in swine as in paragraph (c)(1)(ii) of this section.

(8) 0.6 and 1.6 grams per pound granted to 046573 in § 510.600(c) of this chapter for use in chickens as in paragraph (c)(1)(i) and in swine as in paragraph (c)(1)(ii) of this section.

(b) Related tolerances. See § 556.330 of this chapter.

Hygromycin B in grams per ton	Combination in grams per ton	Indications for use	Limitations	Sponsor
(i) 8 to 12		Chickens: control of infestation of large roundworms (Ascaris galli), cecal worms (Heterakis gallinae), and capillary worms (Capillaria obsignata)	Withdraw 3 days before slaughter	000986,012286, 017790, 043733, 046573
	Bacitracin 100	Chickens; control of infestation of large roundworms (Ascaris galli), cecal worms (Heterakis gallinae), and capillary worms (Capillaria obsignata); treatment of chronic respiratory disease (airsac infection), blue comb (nonspecific infectious enteritis)	As bacitracin methylene disalicylate or zinc bacitracin; withdraw 3 days before slaughter
	Bacitracin plus penicillin (100 to 200 of combination)	1. Chickens; control of infestation of large roundworms (Ascaris galli), cecal worms (Heterakis gallinae), and capillary worms (Capillaria obsignata); treatment of chronic respiratory disease (airsac infection), blue comb (nonspecific infectious enteritis)	Feed containing not less than 25% of penicillin plus not less than 50% of bacitracin; as procaine penicillin plus bacitracin methylene disalicylate; withdraw 3 days before slaughter
	2. Chickens; control of infestation of large roundworms (Ascaris galli), cecal worms (Heterakis gallinae), and capillary worms (Capillaria obsignata); treatment of chronic respiratory disease (airsac infection), blue comb (nonspecific infectious enteritis)	Combination containing not less than 50% nor more than 75% of bacitracin, except that it contains not more than 125 g of penicillin; as procaine penicillin plus zinc bacitracin; withdraw 3 days before slaughter
	3. Chickens, control of infestation of large roundworms (Ascaris galli), cecal worms (Heterakis gallinae), and capillary worms (Capillaria obsignata); treatment of chronic respiratory disease (airsac infection), blue comb (nonspecific infectious enteritis)	Combination containing 50% to 75% bacitracin, but not more than 125 g of penicillin, as procaine penicillin; withdraw 3 days before slaughter.
	Chlortetracycline 100 to 200	Chickens; control of infestation of large roundworms (Ascaris galli), cecal worms (Heterakis gallinae), and capillary worms (Capillaria obsignata); control of infectious synovitis caused by Mycoplasma synoviae susceptible to chlortetracycline	Do not feed to chickens producing eggs for human consumption; feed for 7 to 14 days; withdraw 3 days before slaughter
Code of Federal Regulations 437
	Chlortetracycline 200 to 400	Chickens; control of infestation of large roundworms (Ascaris galli), cecal worms (H. Gallinae), and capillary worms (Capillaria obsignata); control of chronic respiratory disease (CRD) and air sac infection caused by Mycoplasma gallisepticum and Escherichia coli susceptible to chlortetracycline	......do
	Penicillin 100	Chickens; control of infestation of large roundworms (Ascaris galli), cecal worms (Heterakis gallinae), and capillary worms (Capillaria obsignata); treatment of chronic respiratory disease (airsac infection), blue comb (nonspecific infectious enteritis)	As procaine penicillin; withdraw 3 days before slaughter
	Tylosin 4 to 50	Chickens: Control of infestations of large roundworms (Ascaris galli), cecal worms (Heterakis gallinae), and capillary worms (Capillaria obsignata); growth promotion and feed efficiency	As tylosin phosphate; withdraw 3 days before slaughter	000986
(ii) 12		Swine: control of infestation of large roundworms (Ascaris suis), nodular worms (Oesophagostomum dentatum), and whipworms (Trichuris suis)	Withdraw 15 days before slaughter	000986,012286, 017790, 043733, 046573, 051311
	Chlortetracycline 400.	Swine; control of infestation of large roundworms (Ascaris suis), nodular worms (Oesophagostomum dentatum) and whipworms (Trichuris suis); treatment of bacterial enteritis caused by E. coli and Salmonella choleraesuis and bacterial pneumonia caused by P. multocida susceptible to chlortetracycline.	Withdraw 15 d before slaughter.
	Tylosin 10 to 100	Swine: Control of infestations of large roundworms (Ascaris suis), nodular worms (Oesophagostomum dentatum), and whipworms (Trichuris suis); growth promotion and feed efficiency	As tylosin phosphate; withdraw 15 days prior to slaughter; feed continuously as follows:Animal wt.(lbs.): Up to 40........20 to 1001 41 to 100........20 to 401 101 to market wt........10 to 201	000986
1 Amount of Tylosin (g/t).

(2) Hygromycin B may also be used in combination with:

(i) Amprolium in accordance with § 558.55.

(ii) Zoalene in accordance with § 558.680.

Code of Federal Regulations

[41 FR 11000, Mar. 15, 1976]

Code of Federal Regulations

Editorial Note: For Federal Register citations affecting § 558.274 , see the List of CFR Sections Affected, which appears in the Finding Aids section of the printed volume and at www.fdsys.gov.