CFR

520.1320—Mebendazole oral.

(a) Chemical name. Methyl 5-benzoyl-benzimindazole-2-carbamate.

(b) Specifications. As oral powder: Each gram contains either 40 or 166.7 milligrams of mebendazole. As oral paste: Each gram contains 200 milligrams of mebendazole. As oral suspension: Each milliliter contains 33.3 milligrams of mebendazole.

(d) Conditions of use— (1) Horses— 1 gram of mebendazole per 250 pounds of body weight per dose, as an oral powder, paste or suspension.

(ii) Indications for use. It is used in horses for treatment of infections caused by large roundworms (Parascaris equorum ); large strongyles (Strongylus edentatus, S. equinus, S. vulgaris ); small strongyles; and mature and immature (4th larval stage pinworms (Oxyuris equi )).

(iii) Limitations— (a) Oral powder. The drug is given by sprinkling directly on the grain portion of the ration or dissolving in 2 to 4 pints of water and administering by stomach tube. The drug is compatible with carbon disulfide, which can be used concurrently for both control (Gastrophilus spp. ). Routine cautions regarding the use of carbon disulfide must be observed. Do not administer to horses intended for use as food. Federal law restricts this drug to use by or on the order of a licensed veterinarian.

(b) Oral paste. The drug is given by dosing gun (syringe), inserting the tip of the gun at the interdental space in the horse's mouth and depositing the paste on the animal's tongue. The hand is placed under the animal's jaw, and the head is raised to assure that the paste is deposited on the roof of the mouth. Not for use in horses intended for food. Consult your veterinarian for assistance in the diagnosis, treatment, and control of parasitism.

(c) Oral suspension. The drug is administered by stomach tube. Not for horses intended for food use. Federal law restricts this drug to use by or on the order of a licensed veterinarian.

(2) Dogs— (i) Amount. One hundred milligrams of mebendazole per 10 pounds of body weight, once daily for 3 days, as an oral powder.

(ii) Indications for use. The drug is used for treatment of infections of roundworms (Toxocara canis ), hookworms (Ancylostoma caninum, Uncinaria stenocephala ), whipworms (Trichuris vulpis ), and tapeworms (Taenia pisiformis ).

(iii) Limitations. Administer as an oral powder by mixing with a small quantity of food, preferably before the regular meal. Federal law restricts this drug to use by or on the order of a licensed veterinarian.

Code of Federal Regulations

[42 FR 61255, Dec. 2, 1977, as amended at 43 FR 35686, Aug. 11, 1978; 45 FR 3574, Jan. 18, 1980; 46 FR 47218, Sept. 25, 1981; 46 FR 53658, Oct. 30, 1981; 62 FR 61625, Nov. 19, 1997]

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